p38 Kinase Inhibitor 8 is a selective inhibitor of p38β and JNK2α2, demonstrating IC50 values of 6.3 nM and 53.6 nM, respectively. This compound has shown significant anti-inflammatory properties in models of collagen-induced arthritis in rats, making it a valuable tool for research into inflammatory diseases and related signaling pathways. Its orally active nature enhances its practicality for in vivo studies.
p38 Kinase Inhibitor 8 is a selective inhibitor of p38β and JNK2α2, demonstrating IC50 values of 6.3 nM and 53.6 nM, respectively. This compound has shown significant anti-inflammatory properties in models of collagen-induced arthritis in rats, making it a valuable tool for research into inflammatory diseases and related signaling pathways. Its orally active nature enhances its practicality for in vivo studies.
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