Parsaclisib hydrochloride is a selective inhibitor of PI3Kδ, exhibiting an IC50 of 1 nM in the presence of 1 mM ATP. With approximately 20,000-fold selectivity over other PI3K class I isoforms, this orally active compound is valuable for investigating the biochemical pathways involved in B-cell malignancies. It is particularly useful in research focused on relapsed or refractory forms of these cancers.
Parsaclisib hydrochloride is a selective inhibitor of PI3Kδ, exhibiting an IC50 of 1 nM in the presence of 1 mM ATP. With approximately 20,000-fold selectivity over other PI3K class I isoforms, this orally active compound is valuable for investigating the biochemical pathways involved in B-cell malignancies. It is particularly useful in research focused on relapsed or refractory forms of these cancers.
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