Parsaclisib

Catalog No.: A13561

PI3Kδ inhibitor

Parsaclisib

Parsaclisib Chemical Structure

CAS NO. 1426698-88-5

Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.

Availability: In stock

Package Price Qty
5 mg
$450.00
10 mg
$775.00
50 mg
$2,300.00
100 mg
$4,600.00
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Biological Activity

Parsaclisib is a potent and selective PI3Kδ inhibitor, with an IC50 of 1 nM at 1 mM ATP, and shows appr 20,000-fold selectivity for PI3Kα, PI3Kβ, PI3Kγ and 57 other kinases.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.1 mL 115.51 mL 231.01 mL
0.5 mM 4.62 mL 23.1 mL 46.2 mL
1 mM 2.31 mL 11.55 mL 23.1 mL
5 mM 0.46 mL 2.31 mL 4.62 mL

*The above data is based on the productmolecular weight 432.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13561
Actions Inhibitor
CAS No. 1426698-88-5
Formula C20H22ClFN6O2
M. Wt 432.88
Purity >98%
Synonyms INCB050465, INCB-050465, INCB 050465
SMILES CCOC1=C([[email protected]@H](C2)CNC2=O)C(F)=C(Cl)C=C1[[email protected]@H](N3C4=NC=NC(N)=C4C(C)=N3)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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