Pasireotide (diaspartate) is a long-acting somatostatin agonist targeting somatostatin receptors sst1, sst2, sst3, sst4, and sst5, with pKi values of 8.2, 9.0, 9.1, <7.0, and 9.9, respectively. This cyclohexapeptide compound demonstrates significant antisecretory, antiproliferative, and proapoptotic activities. Its diverse biological effects make it a valuable tool for research applications in endocrinology and oncology, particularly in the study of neuroendocrine tumors and hormonal regulation.
Pasireotide (diaspartate) is a long-acting somatostatin agonist targeting somatostatin receptors sst1, sst2, sst3, sst4, and sst5, with pKi values of 8.2, 9.0, 9.1, <7.0, and 9.9, respectively. This cyclohexapeptide compound demonstrates significant antisecretory, antiproliferative, and proapoptotic activities. Its diverse biological effects make it a valuable tool for research applications in endocrinology and oncology, particularly in the study of neuroendocrine tumors and hormonal regulation.
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