Documents & Downloads

Pazopanib-d3 hydrochloride

Stable Isotope

Pazopanib-d3 hydrochloride is a deuterated form of Pazopanib, serving as a stable isotope labeled compound. This multi-targeted inhibitor effectively modulates several receptor tyrosine kinases, including VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms, with respective IC50 values of 10, 30, 47, 84, 74, 140, and 146 nM. Its unique isotopic signature allows for precise tracking and analysis in biological studies, making it suitable for pharmacokinetic research and metabolic studies in oncology and related fields.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	2469755-67-5
Applications	Stable Isotope
Formula	C₂₁H₂₁D₃ClN₇O₂S
Molecular Weight	477.00
Synonyms	GW786034-d3 hydrochloride
SMILES	O=S(C1=CC(NC2=NC=CC(N(C([2H])([2H])[2H])C3=CC4=NN(C)C(C)=C4C=C3)=N2)=CC=C1C)(N)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.