PD 0332991 HCl (Palbociclib)

PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.
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PD 0332991 HCl 5mg
Special Price $40.00 Regular Price $50.00
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PD 0332991 HCl 10mg
Special Price $56.00 Regular Price $70.00
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PD 0332991 HCl 25mg
Special Price $68.00 Regular Price $85.00
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PD 0332991 HCl 50mg
Special Price $80.00 Regular Price $100.00
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Adooq Products cited in reputable paper
Adooq's PD 0332991 HCl (Palbociclib) has been cited by 3 publications
  • Hiroki Ozawa, .et al. , Transl Oncol, 2022, Feb;16:101307 PMID: 34902741
  • Cong Li, .et al. , Mol Cancer Ther., 2015, Feb;14(2):375-83. PMID: 25487917
  • Pirita Pekkonen, .et al. , Cell Cycle, 2014, Dec 1; 13(23): 3670-3684 PMID: 25483078
  • Biological Activity
    Discription PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.
    Targets
    Target Value
    Product Information
    Catalog Num A10701
    Formula C24H29N7O2.HCl
    Molecular Weight 484
    CAS Number 827022-32-2
    SMILES CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 3 mg/mL (6.19 mM)
    Water 30 mg/mL (61.98 mM)
    Ethanol Insoluble
    In vivo Saline 5 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.66 mL 103.31 mL 206.61 mL
    0.5 mM 4.13 mL 20.66 mL 41.32 mL
    1 mM 2.07 mL 10.33 mL 20.66 mL
    5 mM 0.41 mL 2.07 mL 4.13 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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