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PD-149164

CCK-B Receptor Agonist

PD-149164 is a selective agonist of the cholecystokinin B (CCK-B) receptor, exhibiting high binding affinity with IC50 values of 0.083 nM for CCK-B and 75 nM for CCK-A. This compound is instrumental in studying the role of CCK-B receptors in physiological and pathological processes, including appetite regulation, anxiety, and enhanced memory function. It serves as a valuable tool for research in neuropharmacology and gastrointestinal studies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	181941-32-2
Applications	CCK-B Receptor Agonist
Formula	C₃₃H₃₈FN₃O₅
Molecular Weight	575.67
SMILES	O=C(C[C@H](CC1=CC=C(C=C1)F)NC([C@@](NC(OC2C3CC4CC(CC2C4)C3)=O)(C)CC5=CNC6=C5C=CC=C6)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.