PD 169316

Catalog No.: A11221
p38 MAPK inhibitor
PD 169316 (PD169316) is a selective inhibitor of p38 MAPK.1 that inhibits p38 MAPK with an IC50 of 89 nM.
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Biological Activity
Discription PD 169316 (PD169316) is a selective inhibitor of p38 MAPK.1 that inhibits p38 MAPK with an IC50 of 89 nM.
Product Information
Catalog Num A11221
Formula C20H13FN4O2
Molecular Weight 360.3
CAS Number 152121-53-4
SMILES C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)[N+](=O)[O-]
Synonyms PD-169316, PD169316

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO 12 mg/mL (33.3 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.75 mL 138.77 mL 277.55 mL
0.5 mM 5.55 mL 27.75 mL 55.51 mL
1 mM 2.78 mL 13.88 mL 27.75 mL
5 mM 0.56 mL 2.78 mL 5.55 mL
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