PD 175069 is a selective antagonist of N-type calcium channels, exhibiting an IC50 of 0.32 μM. It demonstrates effective inhibition in an audiogenic seizure model with DBA/2 mice, highlighting its potential in the study of neurological conditions. PD 175069 is valuable for research into neuropathic pain and stroke, providing insights into calcium channel modulation in these disorders.
PD 175069 is a selective antagonist of N-type calcium channels, exhibiting an IC50 of 0.32 μM. It demonstrates effective inhibition in an audiogenic seizure model with DBA/2 mice, highlighting its potential in the study of neurological conditions. PD 175069 is valuable for research into neuropathic pain and stroke, providing insights into calcium channel modulation in these disorders.
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