PEG3-bis-(ethyl phosphonate) is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ligases, promoting selective degradation of specific proteins through the ubiquitin-proteasome pathway. Its application extends to various research fields, including drug discovery and functional proteomics, aiding in the development of targeted therapies.
PEG3-bis-(ethyl phosphonate) is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the conjugation of target proteins to E3 ligases, promoting selective degradation of specific proteins through the ubiquitin-proteasome pathway. Its application extends to various research fields, including drug discovery and functional proteomics, aiding in the development of targeted therapies.
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