PF-03394197 (oclacitinib)

Catalog No.: A13082

JAK1 inhibitor

PF-03394197 (oclacitinib)

PF-03394197 (oclacitinib) Chemical Structure

CAS NO. 1208319-26-9

PF-03394197 (oclacitinib) is a potent JAK1 inhibitor

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$200.00
50 mg
$350.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Banovic F, .et al. Immunomodulatory in vitro effects of oclacitinib on canine T-cell proliferation and cytokine production, Vet Dermatol, 2018, Nov 12 PMID: 30417482
  • Nicholas B, .et al. Susceptibility to influenza virus infection of bronchial biopsies in asthma, J Allergy Clin Immunol, 2017, Jul;140(1):309-312.e4 PMID: 28259448
  • Fukuyama T, .et al. Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Impressive Antipruritic and Anti-Inflammatory Responses in a Model of Allergic Dermatitis., J Pharmacol Exp Ther., 2015, Sep;354(3):394-405 PMID: 26159873

Biological Activity

PF-03394197 (oclacitinib) is a potent JAK1 inhibitor
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.63 mL 148.17 mL 296.35 mL
0.5 mM 5.93 mL 29.63 mL 59.27 mL
1 mM 2.96 mL 14.82 mL 29.63 mL
5 mM 0.59 mL 2.96 mL 5.93 mL

*The above data is based on the productmolecular weight 337.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13082
Actions Inhibitor
CAS No. 1208319-26-9
Formula C15H23N5O2S
M. Wt 337.44
Purity >98%
Synonyms PF03394197, PF 03394197
SMILES CNS(=O)(=O)CC1CCC(CC1)N(C)C2=NC=NC3=C2C=CN3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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