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$0.00 - Banovic F, .et al. Immunomodulatory in vitro effects of oclacitinib on canine T-cell proliferation and cytokine production, Vet Dermatol, 2018, Nov 12 PMID: 30417482
- Nicholas B, .et al. Susceptibility to influenza virus infection of bronchial biopsies in asthma, J Allergy Clin Immunol, 2017, Jul;140(1):309-312.e4 PMID: 28259448
- Fukuyama T, .et al. Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Impressive Antipruritic and Anti-Inflammatory Responses in a Model of Allergic Dermatitis., J Pharmacol Exp Ther., 2015, Sep;354(3):394-405 PMID: 26159873
Biological Activity
PF-03394197 (oclacitinib) is a potent JAK1 inhibitor
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.63 mL | 148.17 mL | 296.35 mL |
| 0.5 mM | 5.93 mL | 29.63 mL | 59.27 mL |
| 1 mM | 2.96 mL | 14.82 mL | 29.63 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.93 mL |
*The above data is based on the productmolecular weight 337.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13082 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 337.44 |
| Formula | C15H23N5O2S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1208319-26-9 |
| Synonyms | PF03394197, PF 03394197 |
| SMILES | CNS(=O)(=O)CC1CCC(CC1)N(C)C2=NC=NC3=C2C=CN3 |
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