Catalog No.: A12894

EP2 Receptor antagonist


PF-04418948 Chemical Structure

CAS NO. 1078166-57-0

PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1.

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Biological Activity

PF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1.
EP2 receptor
16 nM
In vitro DMSO 80 mg/mL (195.4 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.43 mL 122.13 mL 244.25 mL
0.5 mM 4.89 mL 24.43 mL 48.85 mL
1 mM 2.44 mL 12.21 mL 24.43 mL
5 mM 0.49 mL 2.44 mL 4.89 mL

*The above data is based on the productmolecular weight 409.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12894
Actions Antagonist
CAS No. 1078166-57-0
Formula C23H20FNO5
M. Wt 409.41
Purity >98%
Synonyms PF04418948, PF 04418948

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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