PF-04677490 is a potent inhibitor of phosphodiesterase 1 (PDE1), with IC50 values of 21 nM, 83 nM, and 118 nM for PDE1B1, PDE1C, and PDE1A, respectively. This compound effectively inhibits the hydrolytic activity of cAMP and cGMP, making it a valuable tool for investigating signaling pathways mediated by cyclic nucleotides. PF-04677490 is suitable for research applications focused on cardiovascular, neurological, and inflammatory diseases.
PF-04677490 is a potent inhibitor of phosphodiesterase 1 (PDE1), with IC50 values of 21 nM, 83 nM, and 118 nM for PDE1B1, PDE1C, and PDE1A, respectively. This compound effectively inhibits the hydrolytic activity of cAMP and cGMP, making it a valuable tool for investigating signaling pathways mediated by cyclic nucleotides. PF-04677490 is suitable for research applications focused on cardiovascular, neurological, and inflammatory diseases.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
