PF-07038124 hydrochloride is a potent phosphodiesterase 4 (PDE4) inhibitor, exhibiting an IC50 of 0.5 nM for the PDE4B2 isoform. This compound displays significant inhibitory effects on pro-inflammatory cytokines, including IL-13, IL-4, and IFNγ, with IC50 values of 125 nM, 4.1 nM, and 1.06 nM, respectively. PF-07038124 hydrochloride serves as a valuable research tool for studying conditions such as atopic dermatitis and plaque psoriasis, aiding in the exploration of therapeutic interventions targeting inflammatory pathways.
PF-07038124 hydrochloride is a potent phosphodiesterase 4 (PDE4) inhibitor, exhibiting an IC50 of 0.5 nM for the PDE4B2 isoform. This compound displays significant inhibitory effects on pro-inflammatory cytokines, including IL-13, IL-4, and IFNγ, with IC50 values of 125 nM, 4.1 nM, and 1.06 nM, respectively. PF-07038124 hydrochloride serves as a valuable research tool for studying conditions such as atopic dermatitis and plaque psoriasis, aiding in the exploration of therapeutic interventions targeting inflammatory pathways.
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