PF-3644022

Catalog No.: A11282

MK2 Inhibitor

PF-3644022

PF-3644022 Chemical Structure

CAS NO. 1276121-88-0

PF-3644022 is a potent and selective mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) inhibitor (Ki =3 nM).

Availability: Out of stock

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5 mg
$150.00
10 mg
$250.00
50 mg
$800.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-3644022 is a potent and selective mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) inhibitor (Ki =3 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.71 mL 133.53 mL 267.05 mL
0.5 mM 5.34 mL 26.71 mL 53.41 mL
1 mM 2.67 mL 13.35 mL 26.71 mL
5 mM 0.53 mL 2.67 mL 5.34 mL

*The above data is based on the productmolecular weight 374.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11282
Actions Inhibitor
CAS No. 1276121-88-0
Formula C21H18N4OS
M. Wt 374.46
Purity >98%
Synonyms PF3644022, PF 3644022
SMILES CC1=NC=C(C2=NC(C=CC(S3)=C4C5=C3C(O)=N[[email protected]](CN5)([H])C)=C4C=C2)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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