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Biological Activity
PF 3716556 is H+,K+-ATPase inhibitor (pIC50 = 6 in human recombinant ion-leaky assays).
Targets
| H+/K+-ATPase | ||||
| ~6.5(pIC50) |
| In vitro | DMSO | 73 mg/mL (185.05 mM) | |
| Water | Insoluble | ||
| Ethanol | 73 mg/mL (185.05 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.35 mL | 126.74 mL | 253.49 mL |
| 0.5 mM | 5.07 mL | 25.35 mL | 50.7 mL |
| 1 mM | 2.53 mL | 12.67 mL | 25.35 mL |
| 5 mM | 0.51 mL | 2.53 mL | 5.07 mL |
*The above data is based on the productmolecular weight 394.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11408 |
|---|---|
| Actions | Antagonist |
| CAS No. | 928774-43-0 |
| Formula | C22H26N4O3 |
| M. Wt | 394.5 |
| Purity | >98% |
| Synonyms | PF-3716556, PF3716556 |
| SMILES | CC1=C2[[email protected]@H](CCOC2=CC=C1)NC3=CC(=CN4C3=NC(=C4)C)C(=O)N(C)CCO |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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