Total item
Cart Subtotal
$0.00 Biological Activity
PF-3758309 is a small-molecule p21-activated kinase inhibitor inhibiting oncogenic signaling and tumor growth.
Targets
| Target | Value |
|---|---|
| PAK4 | IC50: 1.3nM |
| PAK1 | ki: 13.7nM |
| PAK6 | ki: 17.1nM |
| PAK5 | ki: 18.1nM |
| PAK4 | ki: 18.7nM |
| PAK3 | IC50: 99nM |
| PAK2 | IC50: 190nM |
| In vitro | DMSO | 87 mg/mL (177.32 mM) | |
| Water | Insoluble | ||
| Ethanol | 87 mg/mL (177.32 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.4 mL | 102 mL | 204 mL |
| 0.5 mM | 4.08 mL | 20.4 mL | 40.8 mL |
| 1 mM | 2.04 mL | 10.2 mL | 20.4 mL |
| 5 mM | 0.41 mL | 2.04 mL | 4.08 mL |
*The above data is based on the productmolecular weight 490.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11930 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 898044-15-0 |
| Formula | C25H30N8OS |
| M. Wt | 490.2 |
| Purity | >98% |
| Synonyms | PF-03758309 |
| SMILES | CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)N[[email protected]](CN(C)C)C5=CC=CC=C5)SC=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
YM155 (Sepantronium Bromide)
YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.
Birinapant (TL32711)
Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases …
Cyclophosphamide monohydrate
Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing m…
Apoptosis Inhibitor (M50054)
Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis induction.
Nutlin-3
MDM2 antagonist nutlin-3 is a potent inducer of apoptosis.
BV-6
BV-6 is a SMAC mimetic, dual cIAP and XIAP inhibitor.
Tipifarnib (Zarnestra)
Tipifarnib (Zarnestra) is a farnesyltransferase inhibitor that inhibits the Ras kinase in a post translational modification step before the …
Hypothemycin
Hypothemycin is a resorcylic acid lactone polyketide. It was found to inhibit the proliferation of mouse and human T cells stimulated with a…
Keywords:buy PF-3758309 | PF-3758309 Supplier | purchase | cost | manufacturer | order | distributor | buy 898044-15-0| 898044-15-0 Supplier | purchase 898044-15-0 | 898044-15-0 cost | 898044-15-0 manufacturer | order 898044-15-0 | 898044-15-0 distributor
Adooq Quality Guarantee
We promise all products perform as described.