Catalog No.: A11930

PAK4 inhibitor


PF-3758309 Chemical Structure

CAS NO. 898044-15-0

PF-3758309 is a small-molecule p21-activated kinase inhibitor inhibiting oncogenic signaling and tumor growth.

Availability: In stock

Package Price Qty
5 mg
10 mg
25 mg
50 mg
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-3758309 is a small-molecule p21-activated kinase inhibitor inhibiting oncogenic signaling and tumor growth.
Target Value
PAK4IC50: 1.3nM
PAK1ki: 13.7nM
PAK6ki: 17.1nM
PAK5ki: 18.1nM
PAK4ki: 18.7nM
PAK3IC50: 99nM
PAK2IC50: 190nM
In vitro DMSO 87 mg/mL (177.32 mM)
Water Insoluble
Ethanol 87 mg/mL (177.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.4 mL 102 mL 204 mL
0.5 mM 4.08 mL 20.4 mL 40.8 mL
1 mM 2.04 mL 10.2 mL 20.4 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 490.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11930
Actions Inhibitor
CAS No. 898044-15-0
Formula C25H30N8OS
M. Wt 490.2
Purity >98%
Synonyms PF-03758309
SMILES CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)N[[email protected]](CN(C)C)C5=CC=CC=C5)SC=C2

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy PF-3758309 | PF-3758309 Supplier | purchase | cost | manufacturer | order | distributor | buy 898044-15-0| 898044-15-0 Supplier | purchase 898044-15-0 | 898044-15-0 cost | 898044-15-0 manufacturer | order 898044-15-0 | 898044-15-0 distributor