PF-4840154

Catalog No.: A13996

TrpA1 channel agonist

PF-4840154

PF-4840154 Chemical Structure

CAS NO. 1332708-14-1

PF-4840154 is a non-electrophilic reference agonist of the TrpA1 channel. The TRPA1 channel is considered an attractive pain target based on the fact that TRPA1 knockout mice showed near complete attenuation of pain behaviors in some pre-clinical development models.

Availability: In stock

Package Price Qty
5 mg
$400.00
10 mg
$580.00
50 mg
$1,750.00
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Biological Activity

PF-4840154 is a non-electrophilic reference agonist of the TrpA1 channel. The TRPA1 channel is considered an attractive pain target based on the fact that TRPA1 knockout mice showed near complete attenuation of pain behaviors in some pre-clinical development models.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.43 mL 107.15 mL 214.3 mL
0.5 mM 4.29 mL 21.43 mL 42.86 mL
1 mM 2.14 mL 10.72 mL 21.43 mL
5 mM 0.43 mL 2.14 mL 4.29 mL

*The above data is based on the productmolecular weight 466.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13996
Actions Agonist
M. Wt 466.63
Formula C26H38N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1332708-14-1
Synonyms PF 4840154, PF4840154.
SMILES O=C(C1=CN=C(N2CCN(CC3COCCC3)CC2)N=C1NCC(C)C)NCC4=CC=CC=C4

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