PF-4950834

Name: PF-4950834
Brand: Adooq Bioscience
SKU: A24488
Rating: 5 (288 reviews)

Catalog No.: A24488

ROCK inhibitor

PF-4950834 is a potent, selective, and orally bioavailable ATP-competitive inhibitor of Rho-associated kinases, with IC₅₀ values of 8.35 nM for ROCK2 and 33.12 nM for ROCK1. It effectively inhibits neutrophil migration and is suitable for research on inflammation and immune cell regulation.

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PF-4950834 1256264-62-6 <p>ROCK inhibitor</p>

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Grouped product items
Size	Price	Stock
5mg	$360.00	In stock
10mg	$620.00	In stock
50mg	$1,840.00	In stock
100mg	$3,600.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	PF-4950834 is a potent, selective, and orally bioavailable ATP-competitive inhibitor of Rho-associated kinases, with IC₅₀ values of 8.35 nM for ROCK2 and 33.12 nM for ROCK1. It effectively inhibits neutrophil migration and is suitable for research on inflammation and immune cell regulation.

Product Information

Catalog Num	A24488
Formula	C21H19N3O2
Molecular Weight	345.39
CAS Number	1256264-62-6
SMILES	O=C(NC)C1=CC=CC(CNC(C2=CC=C(C3=CC=NC=C3)C=C2)=O)=C1
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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