PF-739 is a potent and orally active activator of AMP-activated protein kinase (AMPK). It effectively stimulates 12 heterotrimeric AMPK complexes, leading to a significant reduction in plasma glucose levels. This compound is utilized in research to investigate metabolic disorders and the cellular responses to energy stress. Its role as a non-selective AMPK activator makes it a valuable tool in studies focused on cellular metabolism and energy homeostasis.
PF-739 is a potent and orally active activator of AMP-activated protein kinase (AMPK). It effectively stimulates 12 heterotrimeric AMPK complexes, leading to a significant reduction in plasma glucose levels. This compound is utilized in research to investigate metabolic disorders and the cellular responses to energy stress. Its role as a non-selective AMPK activator makes it a valuable tool in studies focused on cellular metabolism and energy homeostasis.
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