PF-998425 is a selective nonsteroidal androgen receptor (AR) antagonist, demonstrating significant potency with an IC50 of 37 nM in AR binding assays and 43 nM in cellular assays. This compound exhibits minimal activity towards common receptors and enzymes, such as the progesterone receptor. PF-998425 is relevant for research applications involving sebum control and the investigation of androgenetic alopecia.
PF-998425 is a selective nonsteroidal androgen receptor (AR) antagonist, demonstrating significant potency with an IC50 of 37 nM in AR binding assays and 43 nM in cellular assays. This compound exhibits minimal activity towards common receptors and enzymes, such as the progesterone receptor. PF-998425 is relevant for research applications involving sebum control and the investigation of androgenetic alopecia.
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