PF-AKT400

Catalog No.: A21991

Akt inhibitor

PF-AKT400

PF-AKT400 Chemical Structure

CAS NO. 1004990-28-6

PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM).

Availability: In stock

Package Price Qty
5 mg
$378.00
10 mg
$651.00
50 mg
$1,932.00
100 mg
$3,864.00
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Biological Activity

PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.97 mL 124.87 mL 249.73 mL
0.5 mM 4.99 mL 24.97 mL 49.95 mL
1 mM 2.5 mL 12.49 mL 24.97 mL
5 mM 0.5 mL 2.5 mL 4.99 mL

*The above data is based on the productmolecular weight 400.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21991
Actions Inhibitor
M. Wt 400.43
Formula C20H22F2N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1004990-28-6
Synonyms AKT protein kinase inhibitor; PF-AKT400; PFAKT400; Lig1; Lig-1; Lig 1; PF AKT400; AKT-0286; AKT 0286; AKT0286
SMILES N[[email protected]@](CC1)(CNC(C2=CC=C(F)C=C2F)=O)CN1C3=C4C(NC=C4CC)=NC=N3

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