Total item
Cart Subtotal
$0.00 Biological Activity
PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase.
Targets
| p38α (Cell-free assay) | p38β (Cell-free assay) | |||
| 26 nM | 102 nM |
| In vitro (25°C) | DMSO | 96 mg/mL (201.13 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 7 mg/mL (14.66 mM) | ||
| In vivo | 0.5% methylcellulose/0.2% Tween 80 | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.96 mL | 104.78 mL | 209.56 mL |
| 0.5 mM | 4.19 mL | 20.96 mL | 41.91 mL |
| 1 mM | 2.1 mL | 10.48 mL | 20.96 mL |
| 5 mM | 0.42 mL | 2.1 mL | 4.19 mL |
*The above data is based on the productmolecular weight 477.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11078 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 477.2 |
| Formula | C22H19BrF2N2O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 586379-66-0 |
| Synonyms | PH797804 |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC)N2C(=CC(=C(C2=O)Br)OCC3=C(C=C(C=C3)F)F)C |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
SB 203580
SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.
Pamapimod (R-1503)
Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor.
Vinorelbine (Navelbine)
Vinorelbine is the first 5´NOR semi-synthetic vinca alkaloid. It is obtained by semi-synthesis from alkaloids extracted from the rosy periw…
SD-06
SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibi…
ML-3043
ML-3043 is a p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) a…
DBM 1285 dihydrochloride
DBM 1285 dihydrochloride is a p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF-α production in macrophages and in viv…
VX-745
VX-745 is a small-molecule inhibitor of MAPK that is reported to be active against several isotypes of p38 MAPK, including p38α, p38βand p…
AMG 548
AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blo…
Keywords:buy PH-797804 | PH-797804 Supplier | purchase PH-797804 | PH-797804 cost | PH-797804 manufacturer | order PH-797804 | PH-797804 distributor | buy 586379-66-0| 586379-66-0 Supplier | purchase 586379-66-0 | 586379-66-0 cost | 586379-66-0 manufacturer | order 586379-66-0 | 586379-66-0 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.