Phenylbutazone-d9 is a deuterium-labeled analog of Phenylbutazone, a potent nonsteroidal anti-inflammatory drug (NSAID) that functions as a reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). This compound exhibits significant hepatotoxicity and is known to induce the expression of muscle blind-like protein 1 (MBNL1). Phenylbutazone-d9 is valuable for research applications focused on ankylosing spondylitis and related inflammatory conditions, as well as for studying drug metabolism and pharmacokinetics involving stable isotope labeling.
Phenylbutazone-d9 is a deuterium-labeled analog of Phenylbutazone, a potent nonsteroidal anti-inflammatory drug (NSAID) that functions as a reducing cofactor for the peroxidase activity of prostaglandin H synthase (PHS). This compound exhibits significant hepatotoxicity and is known to induce the expression of muscle blind-like protein 1 (MBNL1). Phenylbutazone-d9 is valuable for research applications focused on ankylosing spondylitis and related inflammatory conditions, as well as for studying drug metabolism and pharmacokinetics involving stable isotope labeling.
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