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PI-3065 is a small molecule and selective inhibitor of p110δ kinase with an Ki value of 1.5nM and IC50 value of 5nM
Targets
| Target | Value |
|---|---|
| p110δ | IC50: 15nM |
| p110β | IC50: 1078nM |
| p110α | IC50: 2299nM |
| mTOR | IC50: 9082nM |
| DNA-PK | IC50: >10000nM |
| p110γ | IC50: 27542nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.74 mL | 98.69 mL | 197.38 mL |
| 0.5 mM | 3.95 mL | 19.74 mL | 39.48 mL |
| 1 mM | 1.97 mL | 9.87 mL | 19.74 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.95 mL |
*The above data is based on the productmolecular weight 506.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14338 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 506.64 |
| Formula | C27H31FN6OS |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 955977-50-1 |
| Synonyms | PI3065, PI 3065 |
| SMILES | C1CC1CN2CCN(CC2)CC3=CC4=C(S3)C(=NC(=N4)C5=C(C=CC6=C5C=CN6)F)N7CCOCC7 |
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Contact information
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