Picropodophyllin-d3

Catalog No.: A32011
Stable Isotope
Picropodophyllin-d3 is a deuterium-labeled derivative of Picropodophyllin, specifically characterized as an insulin-like growth factor-1 receptor (IGF-1R) inhibitor, exhibiting an IC50 of 1 nM. This stable isotope is designed for use in metabolic studies and tracer experiments, providing enhanced sensitivity and precision in research applications. Its selective inhibition of IGF-1R makes it a valuable tool for investigating signaling pathways involved in cancer and metabolic disorders.
Grouped product items
Size Price Stock Qty
1mg
$400.00
In stock
10mg
$3,175.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPicropodophyllin-d3 is a deuterium-labeled derivative of Picropodophyllin, specifically characterized as an insulin-like growth factor-1 receptor (IGF-1R) inhibitor, exhibiting an IC50 of 1 nM. This stable isotope is designed for use in metabolic studies and tracer experiments, providing enhanced sensitivity and precision in research applications. Its selective inhibition of IGF-1R makes it a valuable tool for investigating signaling pathways involved in cancer and metabolic disorders.
Product Information
Catalog NumA32011
FormulaC22H19D3O8
Molecular Weight417.42
CAS Number1454782-81-0
SMILESO=C1[C@@]2([H])[C@@](C3=CC(OC)=C(C(OC)=C3)OC([2H])([2H])[2H])([H])C4=CC(OCO5)=C5C=C4[C@@H]([C@@]2([H])CO1)O
SynonymsAXL1717-d3; Picropodophyllotoxin-d3; PPP-d3
Useful Calculator

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