Piperazin-1-yl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone

Catalog No.: A84177
PROTAC Linker
Piperazin-1-yl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is integral in the design of bifunctional molecules that promote targeted degradation of specific proteins, thereby advancing various research applications in drug discovery and cellular biology. Its unique structure aids in optimizing the efficacy and selectivity of PROTACs in therapeutic contexts.
Grouped product items
Size Price Stock Qty
100mg
$20.00
In stock
250mg
$35.00
In stock
500mg
$45.00
In stock
1g
$65.00
In stock
5g
$150.00
In stock
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPiperazin-1-yl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanone functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is integral in the design of bifunctional molecules that promote targeted degradation of specific proteins, thereby advancing various research applications in drug discovery and cellular biology. Its unique structure aids in optimizing the efficacy and selectivity of PROTACs in therapeutic contexts.
Product Information
Catalog NumA84177
FormulaC17H25BN2O3
Molecular Weight316.21
CAS Number864754-07-4
SMILESO=C(C1=CC=C(C=C1)B2OC(C)(C)C(O2)(C)C)N3CCNCC3
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