Piperlongumine

Catalog No.: A14124
TrxR1/CRM1 inhibitor
Piperlongumine selectively kills cancer cells regardless of p53 status without harming normal cells. It binds to and inihbits proteins known to regulate oxidative stress, in particular, Glutathione S-transferase pi 1 (GSTP1).
Grouped product items
Product Name Price Stock Qty
Piperlongumine 25mg
$90.00
In stock
Piperlongumine 50mg
$150.00
In stock
Piperlongumine 10mM * 1mL in DMSO
$60.00
In stock
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Biological Activity
Discription Piperlongumine selectively kills cancer cells regardless of p53 status without harming normal cells. It binds to and inihbits proteins known to regulate oxidative stress, in particular, Glutathione S-transferase pi 1 (GSTP1).
Targets
Target Value
Product Information
Catalog Num A14124
Formula C17H19NO5
Molecular Weight 317.3
CAS Number 20069-09-4
SMILES COC1=CC(=CC(=C1OC)OC)C=CC(=O)N2CCC=CC2=O
Synonyms Piplartine
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro (25°C) DMSO Warmed: 15 mg/mL (47.26 mM)
Water Insoluble
Ethanol Warmed: 6 mg/mL (18.9 mM)
In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.52 mL 157.58 mL 315.16 mL
0.5 mM 6.3 mL 31.52 mL 63.03 mL
1 mM 3.15 mL 15.76 mL 31.52 mL
5 mM 0.63 mL 3.15 mL 6.3 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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