Pivagabine is a GABA receptor antagonist that acts as a hydrophobic derivative of 4-aminobutyric acid, exhibiting significant neuromodulatory properties. This compound effectively crosses the blood-brain barrier in rodent models, demonstrating its potential for central nervous system research. Pivagabine antagonizes the neuroactive effects triggered by foot shock, influencing GABAA receptor function and modulating corticotropin-releasing factor (CRF) concentrations in the rat brain, thus making it a valuable tool in studies related to stress responses and anxiety.
Pivagabine is a GABA receptor antagonist that acts as a hydrophobic derivative of 4-aminobutyric acid, exhibiting significant neuromodulatory properties. This compound effectively crosses the blood-brain barrier in rodent models, demonstrating its potential for central nervous system research. Pivagabine antagonizes the neuroactive effects triggered by foot shock, influencing GABAA receptor function and modulating corticotropin-releasing factor (CRF) concentrations in the rat brain, thus making it a valuable tool in studies related to stress responses and anxiety.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
