PKCd (8-17) is a bioactive peptide derived from the V1 domain of protein kinase C (PKC)d. This peptide effectively inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Its inhibitory effects on PKCd contribute to reduced ischemic damage in cardiac and cerebral cells, promote fibroblast proliferation, and inhibit graft coronary artery disease in murine models, making it valuable for research in cardiac and cerebrovascular conditions.
PKCd (8-17) is a bioactive peptide derived from the V1 domain of protein kinase C (PKC)d. This peptide effectively inhibits phorbol 12-myristate 13-acetate (PMA)-induced PKCd translocation and activation. Its inhibitory effects on PKCd contribute to reduced ischemic damage in cardiac and cerebral cells, promote fibroblast proliferation, and inhibit graft coronary artery disease in murine models, making it valuable for research in cardiac and cerebrovascular conditions.
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