Gedatolisib (PKI-587)
Catalog No.: A11079
PI3K/mTOR inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's Gedatolisib (PKI-587) has been cited by 1 publications
- Yusuke Murase, .et al. , Oncol Rep, 2022, Apr;47(4):61 PMID: 35088890
Biological Activity
| Description | Gedatolisib (PKI-587) is a highly potent PI3K/mTOR kinase inhibitor that inhibits PI3K-α,β,γ, δ isoforms and mTOR with IC50 of 0.4, 6.0, 5.4, 6.0 and 1.6 nM respectively. | |||||
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| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A11079 |
|---|---|
| Formula | C32H41N9O4 |
| Molecular Weight | 615.7 |
| CAS Number | 1197160-78-3 |
| SMILES | CN(C)C1CCN(CC1)C(=O)C2=CC=C(C=C2)NC(=O)NC3=CC=C(C=C3)C4=NC(=NC(=N4)N5CCOCC5)N6CCOCC6 |
| Synonyms | PKI587, Gedatolisib |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 2 mg/mL (3.24 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.24 mL | 81.21 mL | 162.42 mL |
| 0.5 mM | 3.25 mL | 16.24 mL | 32.48 mL |
| 1 mM | 1.62 mL | 8.12 mL | 16.24 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.25 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
