Pomalidomide-C2-amide-C5-azide is an E3 ligase linker conjugate that targets selected proteins for ubiquitination and degradation via the PROTAC (proteolysis-targeting chimera) approach. This compound demonstrates notable antiproliferative activity and can be utilized in research applications focused on CDK9 modulation. Its design allows for the synthesis of potent PROTAC molecules, advancing studies in targeted protein degradation and cancer therapeutics.
Pomalidomide-C2-amide-C5-azide is an E3 ligase linker conjugate that targets selected proteins for ubiquitination and degradation via the PROTAC (proteolysis-targeting chimera) approach. This compound demonstrates notable antiproliferative activity and can be utilized in research applications focused on CDK9 modulation. Its design allows for the synthesis of potent PROTAC molecules, advancing studies in targeted protein degradation and cancer therapeutics.
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