Pomalidomide-C9-Br is an E3 ligase ligand-linker conjugate designed for the synthesis of PROTAC EGFR degrader 15, a targeted protein degradation agent. This compound exhibits significant anti-cancer activity by promoting the degradation of epidermal growth factor receptor (EGFR) through the proteasome pathway. The use of Pomalidomide-C9-Br in research applications may accelerate the development of novel therapeutics aimed at treating EGFR-driven malignancies.
Pomalidomide-C9-Br is an E3 ligase ligand-linker conjugate designed for the synthesis of PROTAC EGFR degrader 15, a targeted protein degradation agent. This compound exhibits significant anti-cancer activity by promoting the degradation of epidermal growth factor receptor (EGFR) through the proteasome pathway. The use of Pomalidomide-C9-Br in research applications may accelerate the development of novel therapeutics aimed at treating EGFR-driven malignancies.
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