Pomalidomide-PEG2-COOH is an E3 ligase ligand-linker conjugate that incorporates the Pomalidomide moiety known for its interaction with the cereblon protein and a two-unit polyethylene glycol (PEG) linker. This compound is designed for applications in PROTAC (proteolysis-targeting chimera) technology, enabling targeted protein degradation through the recruitment of E3 ubiquitin ligases. Its use facilitates the investigation of protein regulation and the modulation of cellular processes, making it a valuable tool for chemical biology research.
Pomalidomide-PEG2-COOH is an E3 ligase ligand-linker conjugate that incorporates the Pomalidomide moiety known for its interaction with the cereblon protein and a two-unit polyethylene glycol (PEG) linker. This compound is designed for applications in PROTAC (proteolysis-targeting chimera) technology, enabling targeted protein degradation through the recruitment of E3 ubiquitin ligases. Its use facilitates the investigation of protein regulation and the modulation of cellular processes, making it a valuable tool for chemical biology research.
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