Pomalidomide-PEG5-C2-NH2 hydrochloride is a Pomalidomide derivative functioning as a ligand for cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is instrumental in the design of proteolysis-targeting chimeras (PROTACs) through its conjugation with other proteins via a linker. Its applications extend to targeted protein degradation studies and the exploration of CRBN-mediated pathways in cellular models.
Pomalidomide-PEG5-C2-NH2 hydrochloride is a Pomalidomide derivative functioning as a ligand for cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is instrumental in the design of proteolysis-targeting chimeras (PROTACs) through its conjugation with other proteins via a linker. Its applications extend to targeted protein degradation studies and the exploration of CRBN-mediated pathways in cellular models.
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