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Chemical Information
Catalog Num | A10743 |
---|---|
Actions | Inhibitor |
M. Wt | 273.2 |
Formula | C13H11N3O4 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 19171-19-8 |
Synonyms | CC-4047, Actimid |
SMILES code | C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N |
Chemical Name | 4-Amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
Description |
Pomalidomide is a derivative of thalidomide and acts as an immunomodulator. | ||||||||||
Targets |
|
Solubility (25°C) * | In vitro | DMSO | 55 mg/mL (201.28 mM) |
---|---|---|---|
Water | <1 mg/mL (<1 mM) | ||
Ethanol | <1 mg/mL (<1 mM) | ||
In vivo | 1% DMSO/30% polyethylene glycol/1% Tween 80 | 15 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 36.6 mL | 183.02 mL | 366.03mL |
0.5 mM | 7.32 mL | 36.6 mL | 73.21 mL |
1 mM | 3.66 mL | 18.3 mL | 36.6 mL |
5 mM | 0.73 mL | 3.66 mL | 7.32 mL |
*The above data is based on the productmolecular weight 273.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Cat. No. | Product Name | Solubility(mg/mL) | ||
---|---|---|---|---|
Water | DMSO | Ethanol | ||
A10255 | ABT-737 | <1 mg/mL | 163 mg/mL | <1 mg/mL |
A10022 | ABT-263 (Navitoclax) | <1 mg/mL | 195 mg/mL | <1 mg/mL |
A10665 | Obatoclax mesylate (GX15-070) | <1 mg/mL | 83 mg/mL | <1 mg/mL |
A10955 | TW-37 | <1 mg/mL | 115 mg/mL | 4 mg/mL |
A10984 | VX-765 | <1 mg/mL | 102 mg/mL | 102 mg/mL |
A11090 | PAC-1 | <1 mg/mL | 78 mg/mL | 16 mg/mL |
A10491 | JNJ 26854165 | <1 mg/mL | 66 mg/mL | 2 mg/mL |
A11931 | RITA (NSC 652287) | <1 mg/mL | 115 mg/mL | 4 mg/mL |
A10522 | Lenalidomide (CC-5013) | <1 mg/mL | 52 mg/mL | <1 mg/mL |
A10743 | Pomalidomide (CC-4047) | <1 mg/mL | 55 mg/mL | <1 mg/mL |
A11163 | AT-406 | <1 mg/mL | 112 mg/mL | 112 mg/mL |
A11002 | YM155 | 89 mg/mL | 55 mg/mL | 6 mg/mL |
A10935 | Tipifarnib (Zarnestra) | <1 mg/mL | 83 mg/mL | <1 mg/mL |
A10657 | Nutlin-3 | <1 mg/mL | 116 mg/mL | 116 mg/mL |
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