Biological Activity
Ponesimod is an orally active, selective sphingosine-1-phosphate receptor 1 (S1P1) immunomodulator with EC50 of 5.7 nM.
Targets
S1P1 receptor | ||||
5.7 nM(EC50) |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.69 mL | 108.47 mL | 216.93 mL |
0.5 mM | 4.34 mL | 21.69 mL | 43.39 mL |
1 mM | 2.17 mL | 10.85 mL | 21.69 mL |
5 mM | 0.43 mL | 2.17 mL | 4.34 mL |
*The above data is based on the productmolecular weight 460.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13307 |
---|---|
Actions | Modulator |
M. Wt | 460.97 |
Formula | C23H25ClN2O4S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 854107-55-4 |
Synonyms | ACT-128800 |
SMILES | O=C1N(C2=CC=CC=C2C)/C(S/C1=C\C3=CC=C(OC[[email protected]](O)CO)C(Cl)=C3)=N/CCC |
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