PP242 (Torkinib)

PP242 is a potent and selective mTOR inhibitor in both mTORC1 and mTORC2.
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Product Name Price Stock Qty
PP242 5mg
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PP242 10mg
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PP242 50mg
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PP242 100mg
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PP242 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's PP242 (Torkinib) has been cited by 2 publications
  • Hiroshi Fukamachi, .et al. , J Exp Clin Cancer Res, 2019, 38:127 PMID: 30866995
  • Fuse MJ, .et al. , Mol Cancer Ther, 2017, Oct;16(10):2130-2143 PMID: 28751539
  • Biological Activity
    Discription PP242 is a potent and selective mTOR inhibitor in both mTORC1 and mTORC2.
    Target Value
    Product Information
    Catalog Num A10746
    Formula C16H16N6O
    Molecular Weight 308.3
    CAS Number 1092351-67-1
    SMILES CC(C)N1C2=C(/C(=C\3/C=C4C=C(C=CC4=N3)O)/N1)C(=NC=N2)N

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 57 mg/mL (184.86 mM)
    Water Insoluble
    Ethanol 17 mg/mL (55.13 mM)
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 32.44 mL 162.18 mL 324.36 mL
    0.5 mM 6.49 mL 32.44 mL 64.87 mL
    1 mM 3.24 mL 16.22 mL 32.44 mL
    5 mM 0.65 mL 3.24 mL 6.49 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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