PPARγ Agonist 16 acts as a selective agonist for peroxisome proliferator-activated receptor gamma (PPARγ), demonstrating competitive binding to the ligand-binding domain (LBD) with an IC50 of 1790 nM. This compound is notable for its ability to inhibit ear swelling in murine models and shows promising anti-hyperglycemic effects in streptozotocin-induced diabetes models. PPARγ Agonist 16 is valuable for research applications focused on metabolic disorders and inflammation.
PPARγ Agonist 16 acts as a selective agonist for peroxisome proliferator-activated receptor gamma (PPARγ), demonstrating competitive binding to the ligand-binding domain (LBD) with an IC50 of 1790 nM. This compound is notable for its ability to inhibit ear swelling in murine models and shows promising anti-hyperglycemic effects in streptozotocin-induced diabetes models. PPARγ Agonist 16 is valuable for research applications focused on metabolic disorders and inflammation.
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