PPARγ Agonist 17 is a selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It enhances PPARγ activity, leading to cell cycle arrest in the G2/M phase, inhibition of cell migration, and induction of apoptosis in HT-29 colorectal cancer cells. This compound exhibits a broad spectrum of anti-proliferative effects against cancer cells while demonstrating relatively low toxicity in normal cells. Additionally, it is important to note that PPARγ Agonist 17 does not cross the blood-brain barrier, making it suitable for specific research applications.
PPARγ Agonist 17 is a selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It enhances PPARγ activity, leading to cell cycle arrest in the G2/M phase, inhibition of cell migration, and induction of apoptosis in HT-29 colorectal cancer cells. This compound exhibits a broad spectrum of anti-proliferative effects against cancer cells while demonstrating relatively low toxicity in normal cells. Additionally, it is important to note that PPARγ Agonist 17 does not cross the blood-brain barrier, making it suitable for specific research applications.
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