Propargyl-PEG1-acrylate

Catalog No.: A83834
PROTAC Linkers
Propargyl-PEG1-acrylate is a PEG-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an alkyne functional group, it enables efficient click chemistry reactions through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This reagent is crucial for advancing research in targeted protein degradation and other bioconjugation applications.
Grouped product items
Size Price Stock Qty
25mg
$30.00
In stock
50mg
$40.00
In stock
100mg
$65.00
In stock
250mg
$115.00
In stock
1g
$400.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPropargyl-PEG1-acrylate is a PEG-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). Featuring an alkyne functional group, it enables efficient click chemistry reactions through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This reagent is crucial for advancing research in targeted protein degradation and other bioconjugation applications.
Product Information
Catalog NumA83834
FormulaC8H10O3
Molecular Weight154.16
CAS Number52436-42-7
SMILESC=CC(OCCOCC#C)=O
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