Propargyl-PEG2-OH is a PEG-based PROTAC linker that facilitates the synthesis of Thalidomide-O-PEG2-propargyl. This compound contains an alkyne functional group, enabling efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application in research allows for the development of targeted protein degradation strategies, making it a valuable tool for studies in therapeutic intervention and cellular regulation.
Propargyl-PEG2-OH is a PEG-based PROTAC linker that facilitates the synthesis of Thalidomide-O-PEG2-propargyl. This compound contains an alkyne functional group, enabling efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application in research allows for the development of targeted protein degradation strategies, making it a valuable tool for studies in therapeutic intervention and cellular regulation.
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