Propargyl-PEG3-1-o-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite functions as a PEG-based linker in the synthesis of PROTACs. This compound features an alkyne moiety enabling its application in click chemistry, specifically facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. It is particularly useful in targeted protein degradation studies and other research applications requiring precise molecular assembly.
Propargyl-PEG3-1-o-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite functions as a PEG-based linker in the synthesis of PROTACs. This compound features an alkyne moiety enabling its application in click chemistry, specifically facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. It is particularly useful in targeted protein degradation studies and other research applications requiring precise molecular assembly.
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