Propargyl-PEG4-O-C1-NHS ester is a PEG-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an alkyne moiety, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its design is particularly beneficial for research applications in targeted protein degradation, allowing for the precise engineering of therapeutic agents.
Propargyl-PEG4-O-C1-NHS ester is a PEG-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an alkyne moiety, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its design is particularly beneficial for research applications in targeted protein degradation, allowing for the precise engineering of therapeutic agents.
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