Propargyl-PEG4-S-PEG4-Boc

Catalog No.: A83199
PROTAC Linker
Propargyl-PEG4-S-PEG4-Boc is a PEG-based linker specifically designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its alkyne functional group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This reagent is essential for advancing research in targeted protein degradation and connectivity studies in chemical biology.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPropargyl-PEG4-S-PEG4-Boc is a PEG-based linker specifically designed for the synthesis of PROTACs (Proteolysis Targeting Chimeras). Its alkyne functional group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This reagent is essential for advancing research in targeted protein degradation and connectivity studies in chemical biology.
Product Information
Catalog NumA83199
FormulaC26H48O10S
Molecular Weight552.72
CAS Number2055041-18-2
SMILESC#CCOCCOCCOCCOCCSCCOCCOCCOCCOCCC(OC(C)(C)C)=O
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