PROTAC ER Degrader-3

Name: PROTAC ER Degrader-3
SKU: A18519
Price: 374.4 USD
Rating: 5 (288 reviews)

Catalog No.: A18519

PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

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Grouped product items
Product Name	Price	Stock
PROTAC ER Degrader-3 5mg	Special Price $374.40 Regular Price $468.00	In stock
PROTAC ER Degrader-3 10mg	Special Price $644.80 Regular Price $806.00	In stock
PROTAC ER Degrader-3 50mg	Special Price $1,913.60 Regular Price $2,392.00	In stock
PROTAC ER Degrader-3 100mg	Special Price $3,827.20 Regular Price $4,784.00	In stock
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Biological Activity

Discription	PROTAC ER Degrader-3 is an intermediate for synthesis of PAC. PAC, consists the ADCs linker and PROTACs, conjugated to an antibody. PAC extracts from patent WO2017201449A1, compound LP2. PAC conjugated to an antibody is a more marked estrogen receptor-alpha (ERα) degrader compared to PROTAC (without Ab).

Product Information

Catalog Num	A18519
Formula	C71H77N7O12
Molecular Weight	1220.41
CAS Number	2158322-29-1
SMILES	OC1=CC=C(/C(C2=CC=C(OCCN(C)C(COCCOCCNC(C3=CC=C(C(N4[C@@H](C)[C@H](NC([C@H](C)N(C(OC(C)(C)C)=O)C)=O)C(N(CC5=C(OC)C=CC6=C5C=CC=C6)C7=C4C=C(C#N)C=C7)=O)=O)C=C3)=O)=O)C=C2)=C(CC)/C8=CC=CC=C8)C=C1
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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