PROTAC STAT3 degrader-2

Catalog No.: A36599
STAT3 Degrader
PROTAC STAT3 degrader-2 is a highly selective degrader targeting the STAT3 protein with a DC50 value of 3.54 μM in Molm-16 cells. This compound is designed for cancer research applications, facilitating the targeted degradation of STAT3 to investigate its role in tumorigenesis. Additionally, PROTAC STAT3 degrader-2 features an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, providing versatility in experimental designs.
Grouped product items
Size Price Stock Qty
1mg
$155.00
In stock
5mg
$395.00
In stock
10mg
$580.00
In stock
25mg
$905.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPROTAC STAT3 degrader-2 is a highly selective degrader targeting the STAT3 protein with a DC50 value of 3.54 μM in Molm-16 cells. This compound is designed for cancer research applications, facilitating the targeted degradation of STAT3 to investigate its role in tumorigenesis. Additionally, PROTAC STAT3 degrader-2 features an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, providing versatility in experimental designs.
Product Information
Catalog NumA36599
FormulaC59H60F2N9O13P
Molecular Weight1172.13
CAS Number2429877-78-9
SMILESO=C1C2=C(C#CCCCCCC(N3C[C@@H](C(N4[C@@](CC[C@H]4C(N[C@@H](CCC(N)=O)C(NC(C5=CC=CC=C5)C6=CC=CC=C6)=O)=O)([H])CC3)=O)NC(C7=CC8=CC(C(F)(F)P(O)(O)=O)=CC=C8N7)=O)=O)C=CC=C2C(N1C9C(NC(CC9)=O)=O)=O
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