Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
3-(Hydroxymethyl)cyclobutanecarboxylic acid serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances the stability and selectivity of PROTACs, making it a valuable tool for targeted protein degradation studies. Its unique structural properties promote efficient binding and ease of synthesis, contributing to advancements in research applications focused on protein modulation and therapeutic interventions. -
PROTAC Linker
Ethyl 7-aminoheptanoate functions as a PROTAC linker, facilitating the development of PROTAC compounds. This molecule is utilized in the synthesis of proteolysis-targeting chimeras, which promote targeted protein degradation. Its structural properties enable efficient conjugation to various biological entities, making it valuable for research in targeted protein modulation and therapeutic applications. -
PROTAC Linker
15-Aminopentadecanoic acid acts as a PROTAC linker, facilitating the design and synthesis of PROTACs. This compound features a long alkane chain with terminal carboxylic acid and amine groups, allowing for versatile reactivity. The amino group (NH2) readily engages with carboxylic acids, activated NHS esters, and carbonyls to form stable amide bonds, making it an essential reagent for targeted protein degradation research applications. -
PROTAC Linkers
Fmoc-Gly-Gly-Gly-NH-PEG4-C2-COOH is a PEG-derived linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the conjugation of targeting ligands and E3 ligase recruiters, playing a pivotal role in the development of selective protein degradation strategies. Its unique structure enhances solubility and biological compatibility, making it suitable for various applications in drug discovery and research focused on targeted protein degradation mechanisms. -
PROTAC Linker
Methyl 11-aminoundecanoate hydrochloride serves as a PROTAC (Proteolysis Targeting Chimera) linker, facilitating the development of targeted protein degradation strategies. This compound plays a critical role in the synthesis of PROTACs, which are designed to selectively induce the degradation of specific proteins within cellular systems. Its utility in chemical biology and drug discovery enhances its relevance for researchers focused on innovative therapeutic approaches. -
PROTAC Linker
Tert-butyl 4-(2-prop-2-ynoxyethyl)piperazine-1-carboxylate is a specialized PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by linking them to E3 ligases, thereby modulating biological pathways. It is valuable in chemical biology and drug discovery for exploring targeted protein degradation mechanisms. -
PROTAC Linker
N-Methylpropane-1,3-diamine serves as a PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the design and development of targeted protein degradation strategies, enhancing the efficacy of therapeutic agents. Its utility in chemical biology makes it an essential tool for researchers exploring novel approaches in targeted therapy and drug discovery. -
PROTAC Linker
1-(2-(But-3-yn-1-yloxy)ethoxy)-6-chlorohexane serves as a versatile PROTAC linker, facilitating the construction of Proteolysis Targeting Chimeras (PROTACs). This compound enables the selective degradation of target proteins by engaging the ubiquitin-proteasome system. Its unique chemical structure enhances the efficacy of target engagement and modulation in various biochemical applications. Researchers can utilize this linker for advancing studies in targeted protein degradation and related therapeutic strategies. -
PROTAC Linker
6-(Benzyloxycarbonylamino)caproic acid functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the synthesis of these bifunctional molecules, enhancing selectivity and efficacy in targeted protein degradation studies. Applications include research in cancer therapy, drug discovery, and the investigation of protein function through regulated degradation. -
PROTAC Linker
Ph-PEG9-NH2 is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the connection between E3 ligases and target proteins, enabling targeted protein degradation. Its application is crucial in research focused on protein regulation and therapeutic development in oncology and other disease areas. -
PROTAC Linker
Methyl 4-(((tert-butoxycarbonyl)amino)methyl)benzoate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). Its structure facilitates the conjugation of target proteins to E3 ligases, enabling the selective degradation of unwanted proteins within cells. This compound is essential for researchers exploring novel therapeutic approaches in areas such as cancer and neurodegenerative diseases through targeted protein degradation. -
PROTAC Linker
NHBoc-PEG4-methyl acetate is a PROTAC linker designed for the synthesis of proteolysis targeting chimeras (PROTACs). Its flexible PEG4 spacer enhances solubility and bioavailability, facilitating targeted protein degradation. This compound is essential for researchers investigating novel therapeutic strategies involving targeted protein modulation through the use of PROTAC technology. -
PROTAC Linker
Ethyl 3-(piperidin-4-yl)propanoate serves as an efficient PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the ability to design and study targeted protein degradation pathways. Its application in chemical biology research supports advances in therapeutic development and targeted modulation of protein function. -
PROTAC Linker
HS-PEG6-CH2CH2-Boc is a polyethylene glycol (PEG) based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the effective conjugation of target proteins to E3 ligases, enabling selective degradation of intracellular proteins. Its utility in chemical biology makes it valuable for researchers focusing on targeted protein degradation and therapeutic interventions in various disease models. -
PROTAC Linker
(S,R,S)-AHPC-PEG4-tosyl is a PROTAC linker designed for targeted protein degradation applications. Featuring an E3 ligase ligand and a PEG4 spacer, this compound enhances solubility and hydrophilicity, facilitating improved delivery in biological systems. The tosyl group enables reactivity with amines and other nucleophiles, making it a versatile tool in drug research and discovery. -
PROTAC Linker
4-Chloro-1-butyne serves as a potent PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in the synthesis of PROTACs, allowing for targeted degradation of specific proteins in cellular systems. It is particularly useful in studies focused on protein interactions and modulation of cellular pathways. -
PROTAC Linker
4,4'-(Propane-1,3-diylbis(oxy))dianiline serves as an effective PROTAC linker, facilitating the development of PROTAC (proteolysis-targeting chimeras) compounds. By linking a target protein to an E3 ubiquitin ligase, this compound enhances the targeted degradation of specific proteins, making it invaluable for research in cellular regulation and therapeutic development. Its usage is pivotal in studies aimed at understanding protein homeostasis and targeted drug design. -
PROTAC Linker
Tert-Butyl 3-(3-iodopropyl)azetidine-1-carboxylate is an effective PROTAC linker designed for synthesizing Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the degradation of specific proteins by promoting the recruitment of E3 ligases, providing a powerful tool for targeted protein modulation in biological research. It is applicable in studies focused on targeted protein degradation and can aid in the exploration of therapeutic strategies in various disease contexts. -
PROTAC Linker
Methyl 8-oxooctanoate is a versatile PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). It plays a crucial role in the development of novel therapeutic agents by linking target proteins to E3 ligases, thus promoting ubiquitination and degradation. This compound is essential for researchers investigating targeted protein degradation and its implications in various diseases. -
PROTAC Linker
5-Iodopentan-1-ol is a versatile PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in creating potent and selective modulators of protein function by enabling the targeted degradation of specific proteins. It is essential for researchers focused on developing innovative therapeutic strategies in the fields of drug discovery and protein engineering. -
PROTAC Linker
4-Chlorobutyronitrile is a reactive PROTAC linker utilized in the synthesis of proteolysis-targeting chimera (PROTAC) molecules. It facilitates the assembly of bifunctional small molecules designed to selectively degrade target proteins through the ubiquitin-proteasome system. This compound is valuable in the development of targeted protein degradation strategies for various therapeutic applications, including cancer research and neurological disorders. -
PROTAC Linker
Piperidin-4-amine-C5-O-C1 is a PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). It serves as a critical component in the development of bifunctional molecules designed to selectively degrade target proteins via the ubiquitin-proteasome system. This compound enables researchers to explore innovative therapeutic strategies in targeted protein degradation, advancing the field of molecular biology and drug discovery. -
PROTAC Linker
3-(Azetidin-3-yl)propan-1-ol serves as a critical PROTAC linker, facilitating the creation of proteolysis-targeting chimeras (PROTACs). This compound contributes to the selective degradation of target proteins via the ubiquitin-proteasome system. It is utilized in various research applications focused on targeted protein degradation, advancing the understanding of protein function and therapeutic intervention in diseases. -
PROTAC Linker
H2N-PEG4-Hydrazide is a PEG-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of target proteins to E3 ligases, enhancing target degradation through the ubiquitin-proteasome system. H2N-PEG4-Hydrazide is essential for researchers exploring targeted protein degradation approaches in drug discovery and development. -
PROTAC Linker
3-(Methylamino)propanoic acid serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. Its structure is optimized for conjugation, enhancing the efficacy of bioconjugates in research applications focused on protein modulation and cellular control mechanisms. This compound is instrumental in advancing drug discovery efforts aimed at novel therapeutic strategies. -
PROTAC Linker
(S,R,S)-AHPC-PEG4-NHS ester is a PROTAC linker featuring an E3 ligase ligand connected by a PEG4 spacer, enhancing PROTAC drug discovery and development. Its NHS ester functionality allows for efficient coupling with amine-containing molecules, facilitating the formation of targeted protein degradation complexes. The PEG4 spacer further improves the solubility of the conjugated compounds, making this linker a valuable tool in chemical biology research and therapeutic applications. -
PROTAC Linker
14-((tert-Butoxycarbonyl)amino)tetradecanoic acid serves as a versatile PROTAC linker, facilitating the construction of targeted protein degraders. This compound enables the formation of bifunctional molecules that can selectively recruit E3 ligases to target proteins for ubiquitination and subsequent degradation. Its application is pivotal in the development of innovative therapeutics aimed at modulating protein levels and investigating cellular pathways. -
PROTAC Linker
4,4'-(Hexane-1,6-diylbis(oxy))dibenzonitrile serves as a PROTAC linker in the assembly of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of protein ligands, enhancing selective protein degradation in targeted therapeutic applications. Its structural properties make it suitable for the development of innovative treatments in cancer and other diseases. -
PROTAC Linker
Bn-PEG8-OBn is a polyethylene glycol (PEG) linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This versatile linker facilitates the conjugation of target proteins to E3 ligases, enabling selective degradation of proteins of interest. Its application is significant in small molecule drug discovery and biological research, particularly in the development of targeted therapies. -
PROTAC Linker
tert-Butyl 2-(piperidin-4-yl)acetate hydrochloride is a versatile PROTAC linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the recruitment of E3 ligases to target proteins, enabling targeted degradation pathways. Its role in PROTAC development makes it essential for research applications in targeted protein modulation and therapeutic interventions. -
PROTAC Linker
OH-PEG3-Cl is a bifunctional linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This reagent facilitates the conjugation of target proteins to an E3 ligase, enabling the degradation of specific proteins through the ubiquitin-proteasome system. Its application is crucial in chemical biology for the development of targeted protein degradation strategies that can be used in therapeutic research and drug discovery. -
PROTAC Linker
Ethyl 7-oxoheptanoate serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in enhancing the degradation of specific target proteins through the recruitment of E3 ligases. Its application extends to research in targeted protein degradation, making it valuable for studies in cancer biology and other disease mechanisms. -
PROTAC Linker
1-Bromo-4-(4-bromobutyl)benzene acts as an effective PROTAC linker, facilitating the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enables the selective degradation of target proteins by bridging an E3 ligase and a protein of interest, thereby enhancing the efficiency of targeted protein degradation studies. Its utility in the development of novel therapeutic strategies makes it valuable for research in drug discovery and protein regulation. -
PROTAC Linker
3-Cyanocyclobutane-1-carboxylic acid serves as a synthetic linker for PROTAC (proteolysis-targeting chimera) development. This compound facilitates the formation of stable PROTACs, enabling targeted protein degradation by linking a target protein ligand to an E3 ligase ligand. Its unique structural properties make it valuable for research applications in protein modulation and therapeutics. -
PROTAC Linker
Ethyl hex-5-ynoate serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is crucial for researchers aiming to create novel protein degraders that target specific proteins for degradation in cellular systems. Its versatility and effectiveness make it a valuable tool in chemical biology and drug discovery applications. -
PROTAC Linker
tert-Butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)piperazine-1-carboxylate is a specialized linker designed for the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the targeted degradation of specific proteins by bridging E3 ubiquitin ligases with the target protein, enhancing the recruitment and subsequent ubiquitination. It is valuable in research applications focused on protein regulation and therapeutic discovery, particularly in cancer and neurodegenerative diseases. -
PROTAC Linkers
HO-PEG8-CH2COOH is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the conjugation of ligand molecules, enhancing the stability and solubility of PROTACs. HO-PEG8-CH2COOH is essential in chemical biology studies aimed at targeted protein degradation and provides a versatile tool for researchers developing novel therapeutic agents. -
PROTAC Linker
2-Propargyl-(trans)-4-cyclohexanediamine functions as a versatile PROTAC linker, enabling the development of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins through the recruitment of E3 ubiquitin ligases, thereby enhancing the modulation of biological pathways. It is an essential tool in drug discovery and protein regulation research applications. -
PROTAC Linker
3-Hydroxy-2,2,4,4-tetramethylcyclobutan-1-one oxime serves as a versatile PROTAC linker, facilitating the development of targeted protein degradation strategies. It enables the efficient combination of target proteins with E3 ligases, enhancing the design of PROTAC molecules. This compound is pivotal in biochemical research focused on modulating protein levels and exploring therapeutic potentials in various diseases. -
PROTAC Linker
tert-Butyl 4-(3-aminopropyl)piperazine-1-carboxylate serves as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in targeted protein degradation, enhancing the efficacy of therapeutic agents by promoting the ubiquitin-proteasome system. Its unique structure allows for selective degradation of specific proteins, making it a valuable tool in chemical biology and drug discovery research. -
PROTAC Linker
20-Bromoicosanoic acid is a versatile PROTAC linker that facilitates the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the recruitment of E3 ligases to specific target proteins, promoting targeted protein degradation. Its unique structure allows for effective conjugation with various moieties, making it a valuable tool for researchers investigating targeted therapeutics and protein modulation. -
PROTAC Linker
2-(1-benzylpiperidin-4-yl)ethan-1-amine is a versatile PROTAC linker that plays a critical role in the design and synthesis of proteolysis targeting chimeras (PROTACs). This compound facilitates the formation of covalent bonds between E3 ligases and target proteins, enabling targeted degradation of specific proteins within cellular systems. Its application is essential in innovative drug discovery and the study of protein homeostasis and regulation. -
PROTAC Linker
tert-Butyl 6-iodohexanoate serves as a PROTAC linker, facilitating targeted protein degradation through the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in the synthesis of innovative therapeutics designed to selectively degrade unwanted proteins in various biological contexts, thereby advancing drug discovery and development efforts. Its chemical structure enhances conjugation and stability, making it a valuable tool in chemical biology research. -
PROTAC Linker
trans-4-Aminocyclohexanol hydrochloride is a versatile PROTAC linker that facilitates the development of Proteolysis Targeting Chimeras (PROTACs). This compound is instrumental in enabling targeted protein degradation, thereby providing valuable insights into protein function and regulation. Its application in synthetic biology enhances the efficiency of drug discovery and therapeutic development processes. -
PROTAC Linker
2-tert-Butyl 6-methyl 2-azaspiro[3.3]heptane-2,6-dicarboxylate serves as an effective PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is instrumental in enhancing the selective degradation of target proteins via the ubiquitin-proteasome system. Its structural attributes support efficient conjugation to both ligands and E3 ligases, making it a valuable tool in chemical biology and drug discovery applications. -
PROTAC Linker
4-Ethoxycarbonylmethylphenylboronic acid pinacol ester serves as a versatile linker in the synthesis of Proteolysis Targeting Chimeras (PROTACs). By facilitating the assembly of target proteins and E3 ligases, this compound enhances the selective degradation of specific proteins within cellular environments. Its application is crucial in drug discovery and development, particularly for targeting disease-related proteins in cancer and other disorders. -
PROTAC Linker
22-Methoxy-22-oxodocosanoic acid is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by engaging the E3 ubiquitin ligase pathway. It is instrumental in constructing novel therapeutic agents for the modulation of protein levels in various biological research applications. -
PROTAC Linker
Boc-pyrrolidine-cyclopentanamine is a versatile PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs). This compound is essential for the construction of bifunctional molecules that selectively induce the degradation of target proteins via the ubiquitin-proteasome pathway. Its structural features enable optimal interaction with E3 ligases, making it suitable for various research applications in targeted protein degradation studies. -
PROTAC Linker
Methyl 3-cyanopropanoate serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins through the recruitment of E3 ligases, proving essential for targeted protein modulation studies. Its chemical structure supports efficient synthesis and functional application in cellular research, making it valuable for studies in targeted therapy and protein homeostasis. -
PROTAC Linker
N-(3-Hydroxypropyl)carbamic acid benzyl ester serves as an effective PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the recruitment of E3 ligases to specific proteins of interest, thus promoting their ubiquitination and subsequent degradation. Its application is crucial in research focused on targeted protein degradation, providing a strategic approach to modulating protein levels for therapeutic investigation.
