PRT 4165

Catalog No.: A15453

Bmi1/Ring1A inhibitor

PRT 4165

PRT 4165 Chemical Structure

CAS NO. 31083-55-3

PRT 4165 is an inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1). It prevents Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation of topoisomerase 2alpha.

Availability: In stock

Package Price Qty
10 mg
$55.00
25 mg
$110.00
50 mg
$162.00
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Biological Activity

PRT 4165 is an inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1). It prevents Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation of topoisomerase 2alpha.
In vitro DMSO 10 mg/mL (42.51 mM)
Water Insoluble
Ethanol 3 mg/mL (12.75 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 42.51 mL 212.55 mL 425.1 mL
0.5 mM 8.5 mL 42.51 mL 85.02 mL
1 mM 4.25 mL 21.25 mL 42.51 mL
5 mM 0.85 mL 4.25 mL 8.5 mL

*The above data is based on the productmolecular weight 235.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15453
Actions Inhibitor
CAS No. 31083-55-3
Formula C15H9NO2
M. Wt 235.24
Purity >98%
Synonyms PRT4165, PRT-4165
SMILES O=C(C1=CC=CC=C1C/2=O)C2=C\C3=CC=CN=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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