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Publications citing Adooq Products
Prucalopride Citations (1)
- Pierre Meschin,et al. p11 modulates calcium handling through 5-HT?R pathway in rat ventricular cardiomyocytes., Cell Calcium, 2015, Dec;58(6):549-57 26427584
Chemical Information
| Catalog Num | A11771 |
|---|---|
| Actions | Agonist |
| M. Wt | 367.9 |
| Formula | C18H26ClN3O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 179474-81-8 |
| Synonyms | Resolor |
| SMILES code | COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl |
| Chemical Name | 4-Amino-5-chloro-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide |
Description |
Prucalopride is a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalising bowel movements. | ||||||||||||||||||||||||||||||
Targets |
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| Solubility (25°C)* | In vitro | DMSO | 60 mg/mL (163.1 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 38 mg/mL (103.29 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.18 mL | 135.91 mL | 271.81mL |
| 0.5 mM | 5.44 mL | 27.18 mL | 54.36 mL |
| 1 mM | 2.72 mL | 13.59 mL | 27.18 mL |
| 5 mM | 0.54 mL | 2.72 mL | 5.44 mL |
*The above data is based on the productmolecular weight 367.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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