Prucalopride

Catalog No.: A11771

5-HT Receptor agonist

Prucalopride

Prucalopride Chemical Structure

CAS NO. 179474-81-8

Prucalopride is a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalising bowel movements.

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$50.00
25 mg
$90.00
50 mg
$140.00
10mM * 1mL in DMSO
$50.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Pierre Meschin, .et al. p11 modulates calcium handling through 5-HT4R pathway in rat ventricular cardiomyocytes., Cell Calcium, 2015, Dec;58(6):549-57 PMID: 26427584

Biological Activity

Prucalopride is a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalising bowel movements.
Targets
Target Value
5-HT4Aki: 2.5nM
5-HT4Bki: 8nM
5-HT3ki: 3.822μM
5-HT1Aki: >10μM
5-HT1Bki: >10μM
5-HT1Dki: >10μM
5-HT1Eki: >10μM
5-HT1Fki: >10μM
5-HT2Aki: >10μM
5-HT2Bki: >10μM
5-HT2Cki: >10μM
5-HT5Aki: >10μM
5-HT6ki: >10μM
5-HT7ki: >10μM
In vitro DMSO 60 mg/mL (163.1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 38 mg/mL (103.29 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.18 mL 135.91 mL 271.81 mL
0.5 mM 5.44 mL 27.18 mL 54.36 mL
1 mM 2.72 mL 13.59 mL 27.18 mL
5 mM 0.54 mL 2.72 mL 5.44 mL

*The above data is based on the productmolecular weight 367.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11771
Actions Agonist
M. Wt 367.9
Formula C18H26ClN3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 179474-81-8
Synonyms Resolor
SMILES COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Prucalopride | Prucalopride Supplier | purchase | cost | manufacturer | order | distributor | buy 179474-81-8| 179474-81-8 Supplier | purchase 179474-81-8 | 179474-81-8 cost | 179474-81-8 manufacturer | order 179474-81-8 | 179474-81-8 distributor
Rewards