Prucalopride

Catalog No.: A11771

5-HT Receptor agonist

Prucalopride

Prucalopride Chemical Structure

CAS NO. 179474-81-8

Prucalopride is a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalising bowel movements.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $36.00

10 mg

Regular Price: $50.00

Special Price $45.00

25 mg

Regular Price: $90.00

Special Price $81.00

50 mg

Regular Price: $140.00

Special Price $126.00

10mM * 1mL in DMSO

Regular Price: $50.00

Special Price $45.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Prucalopride is a selective, high affinity 5-HT4 receptor agonist which targets the impaired motility associated with chronic constipation, thus normalising bowel movements.
Targets
Target Value
5-HT4Aki: 2.5nM
5-HT4Bki: 8nM
5-HT3ki: 3.822μM
5-HT1Aki: >10μM
5-HT1Bki: >10μM
5-HT1Dki: >10μM
5-HT1Eki: >10μM
5-HT1Fki: >10μM
5-HT2Aki: >10μM
5-HT2Bki: >10μM
5-HT2Cki: >10μM
5-HT5Aki: >10μM
5-HT6ki: >10μM
5-HT7ki: >10μM
In vitro DMSO 60 mg/mL (163.1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 38 mg/mL (103.29 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.18 mL 135.91 mL 271.81 mL
0.5 mM 5.44 mL 27.18 mL 54.36 mL
1 mM 2.72 mL 13.59 mL 27.18 mL
5 mM 0.54 mL 2.72 mL 5.44 mL

*The above data is based on the productmolecular weight 367.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11771
Actions Agonist
M. Wt 367.9
Formula C18H26ClN3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 179474-81-8
Synonyms Resolor
SMILES COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl

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